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macrophages have been examined. It was found that the antiproliferative activity of several alkyl-lysophospholipids was the greatest with a



 

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Biological importance of alkyl-lysophospholipids in mouse-lung macrophages. The antiproliferative effects of alkyl-lysophospholipids on mouse-lung macrophages have been examined. It was found that the antiproliferative activity of several alkyl-lysophospholipids was the greatest with a hexadecyl-lysophospholipid. The cell-cycle analysis showed that the alkyl-lysophospholipid suppressed the entry of the cell into S phase. The alkyl-lysophospholipid was capable of elevating the intracellular concentration of cAMP and inhibiting the protein kinase activity in mouse-lung macrophages.Media playback is unsupported on your device Media caption Will the EU survive? Has the EU delivered? Or has it been a great mistake? The UK's relationship with the EU is "entirely manageable", according to British Foreign Secretary Jeremy Hunt. Asked by the BBC's World at One if the EU was going to survive, Mr Hunt said: "I think the EU is now beyond repair because of the way the French president has behaved." The EU, which controls Britain's border with the Republic of Ireland, refused to allow British negotiators access to the Irish border until new checks are introduced. This prompted fears of a hard border on the island. Irish PM Leo Varadkar said he would refuse to sign a withdrawal deal with the UK without changes to that agreement. Mr Hunt said: "The only way to deal with the Irish border is to put in place a permanent settlement. "We will have to look at that in the future, but that is the way the EU works. The EU is a multi-speed union and it is entirely manageable." The UK is scheduled to leave the EU on 29 March, but both the EU and the UK have agreed to delay that until the end of October, to give more time to come to an agreement. The European Parliament, which is scheduled to be dissolved on 26 May, is expected to hold a vote on whether to approve the Brexit withdrawal deal between the UK and the EU. Mr Hunt said the withdrawal agreement was "the only deal on the table" but the EU was refusing to reopen the withdrawal agreement. He added: "The EU has been pursuing a deliberate strategy of hostility towards the




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